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Protocadherin gamma Subfamily C, 3 (PCDHGC3) (C-Term) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB. Suitable for 人, 大鼠, 小鼠, 豚鼠, 马 和 Cow.
产品编号 ABIN2782183
发货至: 中国

Quick Overview for Protocadherin gamma Subfamily C, 3 (PCDHGC3) (C-Term) 抗体 (ABIN2782183)

抗原

See all Protocadherin gamma Subfamily C, 3 (PCDHGC3) 抗体
Protocadherin gamma Subfamily C, 3 (PCDHGC3)

适用

  • 50
  • 12
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  • 3
  • 2
  • 2
  • 2
  • 1
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人, 大鼠, 小鼠, 豚鼠, 马, Cow

宿主

  • 46
  • 4

克隆类型

  • 47
  • 3
多克隆

标记

  • 19
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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非结合性

应用范围

  • 40
  • 24
  • 13
  • 13
  • 11
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 7
    • 5
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    IKDNGEPSLS TTATLTVSVT EDSPEARAEF PSGSAPREQK KNLTFYLLLS

    预测反应

    Cow: 92%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PCDHGC3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PCDHGC3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 934 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Protocadherin gamma Subfamily C, 3 (PCDHGC3)

    别名

    PCDHGC3

    背景

    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. PCDHGC3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    Alias Symbols: PC43, PCDH-GAMMA-C3, PCDH2
    Protein Interaction Partner: UBC, MFSD3, HGD, APP,
    Protein Size: 934

    分子量

    98 kDa

    基因ID

    5098

    NCBI登录号

    NM_002588, NP_002579

    UniProt

    Q9UN70
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