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Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 518-547), (Middle Region) 抗体

The 兔 多克隆 anti-Protocadherin gamma Subfamily C, 3 antibody is suitable to detect Protocadherin gamma Subfamily C, 3 in samples from 人. It has been validated for WB, FACS, IHC (p) 和 EIA.
产品编号 ABIN954050
发货至: 中国
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Quick Overview for Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 518-547), (Middle Region) 抗体 (ABIN954050)

抗原

See all Protocadherin gamma Subfamily C, 3 (PCDHGC3) 抗体
Protocadherin gamma Subfamily C, 3 (PCDHGC3)

适用

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宿主

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克隆类型

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多克隆

标记

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非结合性

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    AA 518-547, Middle Region

    特异性

    This antibody recognizes PCDHGC3.

    纯化方法

    Purified through a Protein A column followed by peptide affinity purification

    免疫原

    Synthetic peptide - KLH conjugated - corresponding to the central region (between 518-547aa) of human PCDHGC3.

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Protocadherin gamma Subfamily C, 3 (PCDHGC3)

    别名

    PCDHGC3

    背景

    The PCDHGC3 gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.Synonyms: PC-43, PC43, PCDH-gamma-C3, PCDH2, Protocadherin 2, Protocadherin 43, Protocadherin gamma-C3, Protocadherin-2, Protocadherin-43

    分子量

    101077 Da

    基因ID

    5098

    NCBI登录号

    NP_002579
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