SPPL2B 抗体 (N-Term)
(1 reference)Quick Overview for SPPL2B 抗体 (N-Term) (ABIN2782090)
抗原
See all SPPL2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VARGNCTFYE KVRLAQGSGA RGLLIVSRER LVPPGGNKTQ YDEIGIPVAL
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against SPPL2B. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SPPL2B
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anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (N-Term) antibody
SPPL2B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 93-142) antibodySPPL2B 适用: 人, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 492-592) antibodySPPL2B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 196-229) antibodySPPL2B 适用: 人 WB 宿主: 兔 Polyclonal RB53139 unconjugated
anti-Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 126-160) antibodySPPL2B 适用: 人 WB 宿主: 兔 Polyclonal RB53138 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 511 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer's disease." in: Neurobiology of aging, Vol. 35, Issue 7, pp. 1596-604, (2014) (PubMed).
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: "BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer's disease." in: Neurobiology of aging, Vol. 35, Issue 7, pp. 1596-604, (2014) (PubMed).
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- SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
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别名
- SPPL2B
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背景
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SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.
Alias Symbols: IMP4, KIAA1532, MGC111084, PSL1, IMP-4
Protein Size: 511 -
分子量
- 56 kDa
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基因ID
- 56928
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NCBI登录号
- NM_001077238, NP_001070706
抗原
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