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KREMEN1 抗体 (N-Term)

This anti-KREMEN1 antibody is a 兔 多克隆 antibody detecting KREMEN1 in WB. Suitable for 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 犬, 马 和 斑马鱼.
产品编号 ABIN2782050
发货至: 中国

Quick Overview for KREMEN1 抗体 (N-Term) (ABIN2782050)

抗原

See all KREMEN1 抗体
KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

适用

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人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 犬, 马, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This KREMEN1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    LKYPNGEGGL GEHNYCRNPD GDVSPWCYVA EHEDGVYWKY CEIPACQMPG

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against KREMEN1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human KREMEN1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 475 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

    别名

    KREMEN1

    背景

    KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
    Alias Symbols: FLJ31863, KREMEM1, KREMEN, KRM1
    Protein Interaction Partner: DKK1,
    Protein Size: 475

    分子量

    50 kDa

    基因ID

    83999

    NCBI登录号

    NM_001039570, NP_001034659

    UniProt

    C1P671

    途径

    WNT signaling
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