G6PC 抗体 (N-Term)
(3 references)Quick Overview for G6PC 抗体 (N-Term) (ABIN2781769)
抗原
See all G6PC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DFGIQSTRYL QVNYQDSQDW FILVSVIADL RNAFYVLFPI WFHLKETVGI
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 85%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against G6pc. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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anti-Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) antibody
G6PC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149) antibodyG6PC 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB30027 unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) antibodyG6PC 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 82-117) antibodyG6PC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) antibodyG6PC 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 357 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway." in: Molecular and cellular biochemistry, (2023) (PubMed).
: "Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates." in: Nature medicine, Vol. 23, Issue 4, pp. 439-449, (2017) (PubMed).
: "Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling." in: Nature communications, Vol. 7, pp. 10592, (2016) (PubMed).
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: "Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway." in: Molecular and cellular biochemistry, (2023) (PubMed).
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- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
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别名
- G6pc
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背景
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G6pc hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.
Alias Symbols: AW107337, G6Pase, G6pt, Glc-6-Pase
Protein Interaction Partner: Ppargc1a, Foxo1, Sirt1,
Protein Size: 357 -
分子量
- 40 kDa
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基因ID
- 14377
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NCBI登录号
- NM_008061, NP_032087
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UniProt
- P35576
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途径
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
抗原
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