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IRF6 抗体 (C-Term)

This anti-IRF6 antibody is a 兔 多克隆 antibody detecting IRF6 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠 和 绵羊.
产品编号 ABIN2781490
发货至: 中国

Quick Overview for IRF6 抗体 (C-Term) (ABIN2781490)

抗原

See all IRF6 抗体
IRF6 (Interferon Regulatory Factor 6 (IRF6))

适用

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人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, 绵羊

宿主

  • 67
  • 8
  • 1

克隆类型

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  • 15
多克隆

标记

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This IRF6 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    FLSDLIAHQK GQIEKQPPFE IYLCFGEEWP DGKPLERKLI LVQVIPVVAR

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

    产品特性

    This is a rabbit polyclonal antibody against IRF6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human IRF6
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 591 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    IRF6 (Interferon Regulatory Factor 6 (IRF6))

    别名

    IRF6

    背景

    IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
    Alias Symbols: LPS, OFC6, PIT, PPS, VWS, VWS1
    Protein Interaction Partner: HHV8GK18_gp81, UBC, BNC2, IRF5, IRF8, ZBTB3, RFX3, TLX2, LBP,
    Protein Size: 591

    分子量

    65 kDa

    基因ID

    3664

    NCBI登录号

    NM_004661, NP_006138

    UniProt

    O14896
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