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MECP2 抗体 (N-Term)

Name: MECP2 抗体 (N-Term)
SKU: ABIN2781332
Availability: OutOfStock

This anti-MECP2 antibody is a 兔多克隆 antibody detecting MECP2 in WB. Suitable for 人, 小鼠, 大鼠, 马, 犬, Cow 和 Pig. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-MECP2 Antibody Titration: 2. (MECP2 抗体 (N-Term))

1 image

(1 reference)

产品编号 ABIN2781332

发货至: 中国

Quick Overview for MECP2 抗体 (N-Term) (ABIN2781332)

抗原

See all MECP2 抗体

MECP2 (Methyl CpG Binding Protein 2 (MECP2))

适用

人, 小鼠, 大鼠, 马, 犬, Cow, Pig

宿主

兔

克隆类型

多克隆

标记

This MECP2 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product MECP2 Primary Antibody

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N-Term

序列

MVAGMLGLRE EKSEDQDLQG LKEKPLKFKK VKKDKKEDKE GKHEPLQPSA

预测反应

Cow: 91%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 93%

产品特性

This is a rabbit polyclonal antibody against MECP2. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human MECP2
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 7-148) antibody
MECP2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8H4A5B9 unconjugated

anti-Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) antibody
MECP2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B11 unconjugated

anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) antibody
MECP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-100) antibody
MECP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Methyl CpG Binding Protein 2 (MECP2) (pSer423) antibody
MECP2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29261 unconjugated

anti-Methyl CpG Binding Protein 2 (MECP2) (C-Term) antibody
MECP2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Methyl CpG Binding Protein 2 (MECP2) (AA 400-428) antibody
MECP2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB25959 unconjugated

anti-Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) antibody
MECP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4B6 unconjugated

anti-Methyl CpG Binding Protein 2 (MECP2) (N-Term) antibody
MECP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-100) antibody
MECP2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 486 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Zhao, Wu, Bu, Lu, Liang, Cao, Tong, Lu, Wu, Guo et al.: "Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive ..." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 142-53, (2009) (PubMed).
抗原

MECP2 (Methyl CpG Binding Protein 2 (MECP2))

别名

MECP2

背景

Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
Alias Symbols: AUTSX3, DKFZp686A24160, MRX16, MRX79, PPMX, RTS, RTT, RS, MRXSL, MRXS13
Protein Interaction Partner: UBC, HECW2, Hipk2, SOX18, WHSC1, HPDL, XPC, CAT, HIST2H3C, HIST1H4F, HIST2H2BE, HIST2H2AC, CBX3, CBX1, SMC3, YBX1, SIN3A, CBX5, ELAVL1, SUMO2, PPARG, YY1, TERF2, SMARCA2, SOX2, SP1, SP3, LOC407840, CDKL5, PRPF40A, SMARCB1, NCOR1, SKI, HMGB1, SPI1, LBR, RB
Protein Size: 486

分子量

52 kDa

基因ID

4204

NCBI登录号

NM_004992, NP_004983

UniProt

P51608

途径

Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane