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GOT2 抗体 (N-Term)

Cited in 2+ publications. The 兔 多克隆 anti-GOT2 antibody (ABIN2781299) specifically detects GOT2 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 斑马鱼, Cow, 马, 兔, 犬, 豚鼠 和 Saccharomyces cerevisiae samples.
产品编号 ABIN2781299
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GOT2 抗体 (N-Term) (ABIN2781299)

抗原

See all GOT2 抗体
GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

适用

  • 105
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人, 小鼠, 大鼠, 斑马鱼, Cow, 马, 兔, 犬, 豚鼠, Saccharomyces cerevisiae

宿主

  • 97
  • 14
  • 3
  • 1
  • 1
兔

克隆类型

  • 87
  • 27
多克隆

标记

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This GOT2 antibody is un-conjugated

应用范围

  • 86
  • 50
  • 38
  • 25
  • 20
  • 20
  • 14
  • 8
  • 2
  • 2
  • 1
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 13
    • 13
    • 7
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    • 1
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    N-Term

    原理

    GOT2 Antibody - N-terminal region

    序列

    VEMGPPDPIL GVTEAFKRDT NSKKMNLGVG AYRDDNGKPY VLPSVRKAEA

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against GOT2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human GOT2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43517-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." in: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

    Tsai, Hong, Liou, Liao: "Association study of GOT2 genetic polymorphisms and schizophrenia." in: Psychiatric genetics, Vol. 17, Issue 5, pp. 314, (2007) (PubMed).

  • 抗原

    GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

    别名

    GOT2

    背景

    Background Information: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)

    Alternative Symbols: KAT4, DEE82, KATIV, KYAT4, mitAAT

    Protein Name: Aspartate aminotransferase, mitochondrial

    分子量

    45kDa

    基因ID

    2806

    NCBI登录号

    NP_002071

    UniProt

    P00505

    途径

    Monocarboxylic Acid Catabolic Process
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