PAM 抗体 (N-Term)
Quick Overview for PAM 抗体 (N-Term) (ABIN2781297)
抗原
See all PAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PKGVGFRVGG ETGSKYFVLQ VHYGDISAFR DNNKDCSGVS LHLTRLPQPL
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预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PAM. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PAM
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 974 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
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别名
- PAM
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背景
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PAM is a multifunctional protein. It has two enzymatically active domains with catalytic activities-peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products.This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
Alias Symbols: PAL, PHM
Protein Interaction Partner: UBC, CALM1, UHMK1, RASSF9, KALRN, TSC2, PRKCA, TSC1,
Protein Size: 974 -
分子量
- 108 kDa
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基因ID
- 5066
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NCBI登录号
- NM_000919, NP_000910
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UniProt
- A6NMR0
抗原
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