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RRN3 抗体 (Middle Region)

Cited in 1 publication. This 兔 多克隆 anti-RRN3 antibody specifically detects RRN3 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 兔 和 豚鼠 samples.
产品编号 ABIN2781066
发货至: 中国
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Quick Overview for RRN3 抗体 (Middle Region) (ABIN2781066)

抗原

See all RRN3 抗体
RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

适用

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人, 小鼠, 大鼠, 兔, 豚鼠

宿主

  • 26
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克隆类型

  • 29
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多克隆

标记

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This RRN3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    DPIYQVWEDM SAEELQEFKK PMKKDIVEDE DDDFLKGEVP QNDTVIGITP

    预测反应

    Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against RRN3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human RRN3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 651 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Amit, Sela, Keren, Melamed, Muler, Shomron, Izraeli, Ast: "Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene." in: BMC molecular biology, Vol. 8, pp. 109, (2008) (PubMed).

  • 抗原

    RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

    别名

    RRN3

    背景

    RRN3 is RNA polymerase I-specific transcription initiation factor. Phosphorylation of RRN3 by MAPK cascades links cell signaling with the control of gene expression, namely results in rRNA synthesis in turn cell growth.
    Alias Symbols: DKFZp566E104, MGC104238, TIFIA, A-270G1.2
    Protein Interaction Partner: UBC, ACTA1, Polr1e, POLR1B, EIF3L, NMI, RBM15, UBD, Trim28, ELAVL1, TAF1D, POLR1A, MYO1C, TAF1C, TAF1B, TAF1A, UBTF, TBP, PPP2R2A, CDK2, CCNE1, RIBIN, ACTB,
    Protein Size: 651

    分子量

    74 kDa

    基因ID

    54700

    NCBI登录号

    NM_018427, NP_060897

    UniProt

    Q9NYV6

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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