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ZEB2 抗体 (Middle Region)

This anti-ZEB2 antibody is a 兔 多克隆 antibody detecting ZEB2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 马, 豚鼠, Pig 和 斑马鱼. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2780948
发货至: 中国

Quick Overview for ZEB2 抗体 (Middle Region) (ABIN2780948)

抗原

See all ZEB2 抗体
ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

适用

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人, 小鼠, 大鼠, Cow, 马, 豚鼠, Pig, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This ZEB2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    LGRQDGDEEF EEEEEESENK SMDTDPETIR DEEETGDHSM DDSSEDGKME

    预测反应

    Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against ZEB2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ZEB2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1214 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yasumi, Inoue, Maruhashi, Kamachi, Higashi, Kondoh, Uchikawa: "Regulation of trunk neural crest delamination by δEF1 and Sip1 in the chicken embryo." in: Development, growth & differentiation, Vol. 58, Issue 2, pp. 205-14, (2016) (PubMed).

    Guan, Liang, Xie, Li, Liu, Liu, Xiu, Li: "Down-regulation of miR-144 promotes thyroid cancer cell invasion by targeting ZEB1 and ZEB2." in: Endocrine, Vol. 48, Issue 2, pp. 566-74, (2015) (PubMed).

    Rogers, Saxena, Bronner: "Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT." in: The Journal of cell biology, Vol. 203, Issue 5, pp. 835-47, (2013) (PubMed).

  • 抗原

    ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

    别名

    ZEB2

    背景

    The ZFHX1B gene is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins. ZFHX1B is strongly transcribed at an early stage in the developing peripheral and central nervous systems of both mice and humans, in all neuronal regions of the brains of 25-week human fetuses and adult mice, and in numerous nonneural tissues. The SMADIP1 gene (also known as SIP1) is a member of the delta-EF1 (ZEB1, MIM 189909)/Zfh1 family of 2-handed zinc finger/homeodomain proteins. SMADIP1 interacts with receptor-mediated, activated full-length SMADs (see MIM 605568) (Verschueren et al., 1999 [PubMed 10400677]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-58 AB056507.1 1-58 59-553 AL118674.1 57-551 554-5558 AB056507.1 553-5557 5559-5583 AI858477.1 1-25 c
    Alias Symbols: KIAA0569, SIP-1, SIP1, SMADIP1, ZFHX1B, HSPC082
    Protein Interaction Partner: CTBP1, SOX2, SMAD9, SMAD3, SMAD2, SMAD1, APP, HDAC4, CBX4, SUMO1, UBE2I, ELAVL1, UBC, MTA2, MTA1, RBBP7, RBBP4, HDAC2, HDAC1, CEBPA, COPS6, SMAD5, CTBP2,
    Protein Size: 1214

    分子量

    136 kDa

    基因ID

    9839

    NCBI登录号

    NM_014795, NP_055610

    UniProt

    O60315

    途径

    Tube Formation
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