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IKZF3 抗体 (C-Term)

IKZF3 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780887
发货至: 中国
  • 抗原 See all IKZF3 抗体
    IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
    抗原表位
    • 15
    • 9
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 62
    • 33
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼
    宿主
    • 51
    • 12
    克隆类型
    • 52
    • 11
    多克隆
    标记
    • 37
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IKZF3 antibody is un-conjugated
    应用范围
    • 58
    • 28
    • 13
    • 13
    • 11
    • 10
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    LDYVMFTIHM GCHGFRDPFE CNMCGYRSHD RYEFSSHIAR GEHRALLK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against IKZF3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human IKZF3
    Top Product
    Discover our top product IKZF3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 509 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
    别名
    IKZF3 (IKZF3 产品)
    别名
    AIO antibody, AIOLOS antibody, ZNFN1A3 antibody, aio antibody, aiolos antibody, znfn1a3 antibody, IKZF3 antibody, 5830411O07Rik antibody, Aiolos antibody, Zfpn1a3 antibody, Znfn1a3 antibody, IKAROS family zinc finger 3 antibody, IKAROS family zinc finger 3 L homeolog antibody, IKZF3 antibody, ikzf3.L antibody, Ikzf3 antibody
    背景
    IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
    Alias Symbols: AIOLOS, ZNFN1A3, AIO
    Protein Interaction Partner: STAMBPL1, EXOSC5, LGALS14, CABP5, PCID2, RCOR3, TBC1D22B, FANCL, MAGOHB, C1orf109, OAZ3, SPG21, CHCHD2, OSGIN1, POLM, PPP1R16B, ABLIM3, IKZF3, NEK6, FARS2, MRPL28, KAT5, BCAS2, AKAP9, FAM115A, EMC2, POLR1C, STX11, STK16, RAD51D, PSMA1, PRKAB2, PRKAA1, PIN
    Protein Size: 509
    分子量
    58 kDa
    基因ID
    22806
    NCBI登录号
    NM_012481, NP_036613
    UniProt
    Q9UKT9
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