ZBTB33 抗体 (N-Term)
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Quick Overview for ZBTB33 抗体 (N-Term) (ABIN2780808)
抗原
See all ZBTB33 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MESRKLISAT DIQYSGSLLN SLNEQRGHGL FCDVTVIVED RKFRAHKNIL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against ZBTB33. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZBTB33
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 672 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))
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别名
- ZBTB33
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背景
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ZBTB33 is a transcriptional regulator with bimodal DNA-binding specificity. ZBTB33 binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. ZBTB33 recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway. It may also activate transcription of a subset of target genes by the recruitment of CTNND2.
Alias Symbols: ZNF348, ZNF-kaiso
Protein Interaction Partner: HUWE1, SUMO2, SUMO3, CBFA2T3, LMNA, UBC, TCF7L2, KPNA2, CTNND1, CTNNB1, CTCF, ELAVL1, CTNND2, WDR48, NCOR1, ZBTB33, HDAC3, WNT11, S100A4, MMP7,
Protein Size: 672 -
分子量
- 74 kDa
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基因ID
- 10009
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NCBI登录号
- NM_006777, NP_006768
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UniProt
- Q86T24
抗原
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