HIC1 抗体 (Middle Region)
(1 reference)Quick Overview for HIC1 抗体 (Middle Region) (ABIN2780783)
抗原
See all HIC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- GETPIAVMGE FANLATSLNP LDPDKDEEEE EEEESEDELP QDISLAAGGE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against HIC1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HIC1
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anti-Hypermethylated in Cancer 1 (HIC1) (AA 396-453) antibody
HIC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Hypermethylated in Cancer 1 (HIC1) (AA 396-453) antibodyHIC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Hypermethylated in Cancer 1 (HIC1) (AA 297-418) antibodyHIC1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 1 (HIC1) (AA 193-204) antibodyVerified HIC1 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Hypermethylated in Cancer 1 (HIC1) (AA 899-948) antibodyHIC1 适用: 人, 豚鼠, 犬, Cow, Pig, 猴, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 1 (HIC1) (AA 627-705) antibodyHIC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Hypermethylated in Cancer 1 (HIC1) (AA 215-264) antibodyHIC1 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 1 (HIC1) (AA 209-258) antibodyHIC1 适用: 人, 小鼠, 大鼠, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 1 (HIC1) (AA 180-430) antibodyHIC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 714 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma." in: Oncogene, Vol. 27, Issue 18, pp. 2613-25, (2008) (PubMed).
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: "Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma." in: Oncogene, Vol. 27, Issue 18, pp. 2613-25, (2008) (PubMed).
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- HIC1 (Hypermethylated in Cancer 1 (HIC1))
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别名
- HIC1
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背景
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HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.
Alias Symbols: ZBTB29, hic-1, ZNF901
Protein Interaction Partner: PIAS4, PIAS3, PIAS2, SP1, STAT3, SIRT1, MTA1, UBE2I, SUMO2, HIC2, TCF4, CTBP2, CTBP1, EED, PHF1, EZH2, PHF19, SUZ12, UBC, MBD3, RBBP4, CHD3, SENP3, HDAC4, PIAS1, ARID1A, HIC1, HDAC1,
Protein Size: 714 -
分子量
- 74 kDa
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基因ID
- 3090
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NCBI登录号
- NM_006497, NP_006488
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UniProt
- Q14526
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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