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HIC1 抗体 (N-Term)

HIC1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777507
发货至: 中国
  • 抗原 See all HIC1 抗体
    HIC1 (Hypermethylated in Cancer 1 (HIC1))
    抗原表位
    • 15
    • 9
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 30
    • 20
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, 豚鼠, Cow, Pig
    宿主
    • 42
    • 4
    • 1
    克隆类型
    • 43
    • 4
    多克隆
    标记
    • 20
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIC1 antibody is un-conjugated
    应用范围
    • 43
    • 23
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    RRCSPLCGLD LSKKSPPGSA APERPLAERE LPPRPDSPPS AGPAAYKEPP
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 85%
    产品特性
    This is a rabbit polyclonal antibody against HIC1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human HIC1
    Top Product
    Discover our top product HIC1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 714 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Stöcklein, Smardova, Macak, Katzenberger, Höller, Wessendorf, Hutter, Dreyling, Haralambieva, Mäder, Müller-Hermelink, Rosenwald, Ott, Kalla: "Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma." in: Oncogene, Vol. 27, Issue 18, pp. 2613-25, (2008) (PubMed).

  • 抗原
    HIC1 (Hypermethylated in Cancer 1 (HIC1))
    别名
    HIC1 (HIC1 产品)
    别名
    zfHIC1 antibody, HIC1 antibody, ZBTB29 antibody, ZNF901 antibody, hic-1 antibody, AA408311 antibody, HIC-1 antibody, hypermethylated in cancer 1 antibody, HIC ZBTB transcriptional repressor 1 antibody, hic1 antibody, HIC1 antibody, Hic1 antibody
    背景
    HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for liss
    Alias Symbols: ZBTB29, hic-1, ZNF901
    Protein Interaction Partner: PIAS4, PIAS3, PIAS2, SP1, STAT3, SIRT1, MTA1, UBE2I, SUMO2, HIC2, TCF4, CTBP2, CTBP1, EED, PHF1, EZH2, PHF19, SUZ12, UBC, MBD3, RBBP4, CHD3, SENP3, HDAC4, PIAS1, ARID1A, HIC1, HDAC1,
    Protein Size: 714
    分子量
    74 kDa
    基因ID
    3090
    NCBI登录号
    NM_006497, NP_006488
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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