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PPARD 抗体 (N-Term)

PPARD 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780757
发货至: 中国
  • 抗原 See all PPARD 抗体
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    抗原表位
    • 16
    • 13
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    • 1
    • 1
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    • 1
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    N-Term
    适用
    • 82
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    • 6
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    • 5
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    人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, Saccharomyces cerevisiae
    宿主
    • 79
    • 10
    • 1
    克隆类型
    • 81
    • 9
    多克隆
    标记
    • 45
    • 11
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    This PPARD antibody is un-conjugated
    应用范围
    • 80
    • 41
    • 28
    • 15
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
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    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MEQPQEEAPE VREEEEKEEV AEAEGAPELN GGPQHALPSS SYTDLSRSSS
    预测反应
    Cow: 80%, Dog: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%, Yeast: 90%
    产品特性
    This is a rabbit polyclonal antibody against PPARD. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the n terminal region of human PPARD
    Top Product
    Discover our top product PPARD Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 441 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    别名
    PPARD (PPARD 产品)
    别名
    FAAR antibody, NR1C2 antibody, NUC1 antibody, NUCI antibody, NUCII antibody, PPARB antibody, NUC-1 antibody, Nr1c2 antibody, PPAR-beta antibody, PPAR-delta antibody, PPAR[b] antibody, PPARdelta antibody, Pparb antibody, Pparb/d antibody, PPARBETA antibody, ppard antibody, pparb antibody, PPARD antibody, PPAR-D/B antibody, peroxisome proliferator activated receptor delta antibody, peroxisome proliferator activator receptor delta antibody, peroxisome proliferator activated receptor delta S homeolog antibody, peroxisome proliferator-activated receptor delta antibody, PPARD antibody, Ppard antibody, ppard.S antibody, ppard antibody
    背景
    PPARD is a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR delta and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation.
    Alias Symbols: FAAR, MGC3931, NR1C2, NUC1, NUCI, NUCII, PPAR-beta, PPARB
    Protein Interaction Partner: KRTAP10-3, KRTAP10-7, PLA2G4A, CTNNB1, KDM1A, PRMT3, SMAD9, HSP90AA1, TNP1, PSMG1, Nedd4, RANBP9, PRDX6, EIF3I, NCOA1, NR0B2, SHMT2, RXRG, RXRB, RXRA, PROX1, ITGB5, GLUL, RELA, HDAC1, EP300, NCOA2, SRC, SPEN, HDAC7, HDAC3, PEBP1, HDAC2, GADD45G, GADD45B,
    Protein Size: 441
    分子量
    49 kDa
    基因ID
    5467
    NCBI登录号
    NM_001039694, NP_001034783
    途径
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
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