NKX3-1 抗体 (Middle Region)
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北京 101111
Quick Overview for NKX3-1 抗体 (Middle Region) (ABIN2780751)
抗原
See all NKX3-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- NKX3-1 Antibody - middle region
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序列
- FSHQKYLSAP ERAHLAKNLK LTETQVKIWF QNRRYKTKRK QLSSELGDLE
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against NKX3-1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NKX3-1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38751-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
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别名
- NKX3-1
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背景
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Background Information: The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: NK3 homeobox 1
Alternative Symbols: NKX3, BAPX2, NKX3A, NKX3.1
Protein Name: Homeobox protein Nkx-3.1
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分子量
- 26kDa
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基因ID
- 4824
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NCBI登录号
- NP_006158
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UniProt
- Q99801
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
抗原
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