HDAC6 抗体 (C-Term)
Quick Overview for HDAC6 抗体 (C-Term) (ABIN2780739)
抗原
See all HDAC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VCHHEASEHP LVLSCVDLST WCYVCQAYVH HEDLQDVKNA AHQNKFGEDM
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against Hdac6. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hdac6
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1149 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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别名
- Hdac6
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背景
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Hdac6 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Hdac6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Alias Symbols: Hd6, Hdac5, Sfc6, mHDA2
Protein Interaction Partner: Hdac11, Ubc, Hsp90ab1, Park2, TARDBP, Vcp, USP47, HDAC6, PLAA, GARS, Tuba1a, Rela, Nfkb1, Mapt,
Protein Size: 1149 -
分子量
- 126 kDa
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基因ID
- 15185
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NCBI登录号
- NM_010413, NP_034543
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UniProt
- Q9Z2V5
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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