MECOM 抗体 (N-Term)
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北京 101111
Quick Overview for MECOM 抗体 (N-Term) (ABIN2780631)
抗原
See all MECOM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- MDS1 Antibody - N-terminal region
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序列
- MRSKGRARKL ATNNECVYGN YPEIPLEEMP DADGVASTPS LNIQEPCSPA
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预测反应
- Human: 100%, Mouse: 93%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against MDS1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MDS1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38536-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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别名
- MDS1
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背景
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Background Information: MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
Gene Name: Myelodysplasia syndrome 1
Alternative Symbols: PRDM3, MDS1-EVI1
Protein Name: MDS1 and EVI1 complex locus protein MDS1
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分子量
- 19kDa
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基因ID
- 4197
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NCBI登录号
- NP_004982
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UniProt
- Q13465
抗原
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