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MECOM 抗体 (N-Term)

This anti-MECOM antibody is a 兔 多克隆 antibody detecting MECOM in WB. Suitable for 人, 小鼠 和 斑马鱼.
产品编号 ABIN2780631
发货至: 中国
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Quick Overview for MECOM 抗体 (N-Term) (ABIN2780631)

抗原

See all MECOM 抗体
MECOM (MDS1 and EVI1 Complex Locus (MECOM))

适用

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  • 1
人, 小鼠, 斑马鱼

宿主

  • 47
  • 14
  • 1

克隆类型

  • 50
  • 12
多克隆

标记

  • 37
  • 5
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  • 3
  • 1
  • 1
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This MECOM antibody is un-conjugated

应用范围

  • 45
  • 35
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Western Blotting (WB)
  • 抗原表位

    • 11
    • 9
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    • 5
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    • 2
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    • 1
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    • 1
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    • 1
    N-Term

    序列

    MRSKGRARKL ATNNECVYGN YPEIPLEEMP DADGVASTPS LNIQEPCSPA

    预测反应

    Human: 100%, Mouse: 93%, Zebrafish: 77%

    产品特性

    This is a rabbit polyclonal antibody against MDS1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human MDS1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 169 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MECOM (MDS1 and EVI1 Complex Locus (MECOM))

    别名

    MDS1

    背景

    MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
    Alias Symbols: PRDM3, MDS1-EVI1
    Protein Size: 169

    分子量

    19 kDa

    基因ID

    4197

    NCBI登录号

    NM_004991, NP_004982

    UniProt

    Q13465
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