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HDAC1 抗体 (N-Term)

This anti-HDAC1 antibody is a 兔 多克隆 antibody detecting HDAC1 in WB. Suitable for 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马 和 斑马鱼.
产品编号 ABIN2780628
发货至: 中国

Quick Overview for HDAC1 抗体 (N-Term) (ABIN2780628)

抗原

See all HDAC1 抗体
HDAC1 (Histone Deacetylase 1 (HDAC1))

适用

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人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This HDAC1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    CYYYDGDVGN YYYGQGHPMK PHRIRMTHNL LLNYGLYRKM EIYRPHKANA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against HDAC1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human HDAC1
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HDAC1 (Histone Deacetylase 1 (HDAC1))

    别名

    HDAC1

    背景

    Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
    Alias Symbols: GON-10, HD1, RPD3, RPD3L1
    Protein Interaction Partner: BCL6, CUL4B, YY1, SIN3A, RCOR1, KDM1A, KAT5, NCOR2, SUMO1, DDIT3, DDB1, BCOR, SF3A1, TP53, SP1, SUMO2, NFKB1, NFE2L2, MDM2, SMAD3, SMAD1, JUN, CHFR, HIF1A, HDAC2, EP300, SAP130, UBC, RELA, RB1, RARA, PRDM6, HAUS2, FEZF2, BANP, WHSC1, ESR1, DNMT3B, DNMT1,
    Protein Size: 482

    分子量

    55 kDa

    基因ID

    3065

    NCBI登录号

    NM_004964, NP_004955

    UniProt

    Q13547

    途径

    Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
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