NOTCH4 抗体 (C-Term)
Quick Overview for NOTCH4 抗体 (C-Term) (ABIN2780608)
抗原
See all NOTCH4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- CDWVALGACG SASNIPIPPP CLTPSPERGS PQLDCGPPAL QEMPINQGGE
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预测反应
- Cow: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against NOTCH4. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NOTCH4
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anti-Notch 4 (NOTCH4) (AA 1715-2001) antibody
NOTCH4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (Middle Region) antibodyNOTCH4 适用: 人, 大鼠, Cow, 马, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) antibodyNOTCH4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 371-420) antibodyNOTCH4 适用: 人, Cow, 马, 豚鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 1261-1273) antibodyVerified NOTCH4 适用: 人, 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 1824-2003) antibodyNOTCH4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (Middle Region) antibodyNOTCH4 适用: 人, Cow, 马, 豚鼠, Pig, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (Cleaved-Val1432) antibodyNOTCH4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (C-Term) antibodyNOTCH4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 1819-1851), (C-Term) antibodyNOTCH4 适用: 人 WB 宿主: 兔 Polyclonal RB52895 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 2003 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NOTCH4 (Notch 4 (NOTCH4))
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别名
- NOTCH4
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背景
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NOTCH4 is a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. NOTCH4 is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. NOTCH4 functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. NOTCH4 gene may be associated with susceptibility to schizophrenia in a small portion of cases.
Alias Symbols: INT3, NOTCH4
Protein Interaction Partner: EGFL7, Dlg4, SMAD4, SMAD3, SMAD2, TCEB1, UBC, TP53, MDM2, MAML3, MAML2, FBXW7, MAML1, DLL4, PSEN2, NOTCH4, RBPJ, PSEN1,
Protein Size: 2003 -
分子量
- 58 kDa
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基因ID
- 4855
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NCBI登录号
- NM_004557, NP_004548
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UniProt
- Q99466
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途径
- Notch Signaling
抗原
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