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ZNF259 抗体 (N-Term)

This anti-ZNF259 antibody is a 兔 多克隆 antibody detecting ZNF259 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 和 斑马鱼.
产品编号 ABIN2780557
发货至: 中国

Quick Overview for ZNF259 抗体 (N-Term) (ABIN2780557)

抗原

See all ZNF259 (znf259) 抗体
ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 32
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克隆类型

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多克隆

标记

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This ZNF259 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    PPGAAVAPSP APAPPPAPDH LFRPISAEDE EQQPTEIESL CMNCYCNGMT

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against ZNF259. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF259
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 459 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

    别名

    ZNF259

    背景

    ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. ZNF259 binds to the EGFR and is released from the receptor after activation.ZNF259 is essential for cell viability and its interaction with eEF-1alpha contributes to normal cellular proliferation.ZNF259 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. ZNF259 accumulates in the nucleolus of proliferating cells. Loss of ZNF259 caused disruption of nucleolar function, including preribosomal RNA expression. ZNF259 is an essential protein that is required for normal nucleolar function in proliferating cells.
    Alias Symbols: ZPR1
    Protein Interaction Partner: UBC, P3H1, FKBP10, RPRD1B, OSGEP, PPME1, SZRD1, ARIH1, HSPBP1, ACTR2, ACTR3, ARPC4, UBA2, TOM1L1, OGT, SURF2, PPP1R7, LPP, HSF1, AGFG1, HNRNPF, BAG1, ALAD, MPP3, SRXN1, NUDCD2, UBL7, THOC7, KLC2, UBQLN4, UFM1, UFC1, UBXN1, UHRF1, PHPT1, TES, UBXN7, HYPK,
    Protein Size: 459

    分子量

    51 kDa

    基因ID

    8882

    NCBI登录号

    NM_003904, NP_003895

    UniProt

    O75312
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