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RFX1 抗体 (N-Term)

This anti-RFX1 antibody is a 兔 多克隆 antibody detecting RFX1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig, 马 和 兔.
产品编号 ABIN2780453
发货至: 中国

Quick Overview for RFX1 抗体 (N-Term) (ABIN2780453)

抗原

See all RFX1 抗体
RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig, 马, 兔

宿主

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克隆类型

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多克隆

标记

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This RFX1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    PQPPQPPTAA ATPQPQYVTE LQSPQPQAQP PGGQKQYVTE LPAVPAPSQP

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against RFX1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human RFX1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 979 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

    别名

    RFX1

    背景

    This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX1 is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: EF-C, EFC, RFX
    Protein Interaction Partner: SOX2, SMAD9, SMAD4, SMAD1, NOTCH1, Cebpb, NCOA3, HDAC1, NFIC, NFIB, TADA3, RFX3, MAGED1, ABL1, NFIX, HMGB1, HIVEP2, RFX2, ADD1,
    Protein Size: 979

    分子量

    105 kDa

    基因ID

    5989

    NCBI登录号

    NM_002918, NP_002909

    UniProt

    P22670

    途径

    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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