Phospholipase D2 抗体 (N-Term)
Quick Overview for Phospholipase D2 抗体 (N-Term) (ABIN2780445)
抗原
See all Phospholipase D2 (PLD2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MTATPESLFP TGDELDSSQL QMESDEVDTL KEGEDPADRM HPFLAIYELQ
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预测反应
- Cow: 86%, Dog: 85%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Mouse: 75%, Rabbit: 86%, Rat: 75%
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产品特性
- This is a rabbit polyclonal antibody against PLD2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PLD2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 933 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Phospholipase D2 (PLD2)
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别名
- PLD2
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背景
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Phosphatidylcholine (PC)-specific phospholipases D (PLDs, EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.Phosphatidylcholine (PC)-specific phospholipases D (PLDs, EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-14 AF033850.1 61-74 15-614 BC015033.1 1-600 615-1279 BC056871.1 549-1213 1280-1830 BC015033.1 1266-1816 1831-1995 BC056871.1 1765-1929 1996-3489 BC015033.1 1982-3475
Alias Symbols: -
Protein Interaction Partner: UBC, RPS6KB1, CUL3, AQP3, RPTOR, PEA15, PIP5K1A, STXBP1, DPYSL2, BIN1, MTOR, CAV1, AMPH, OPRM1, ALDOC, GM2A, PRKCD, PRKCA, PLCG1, LCK, GAPDH, FYN, EGFR, CSK, ALDOA, ARF1, ACTB, ACTN1, CAV2, SRC,
Protein Size: 933 -
分子量
- 106 kDa
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基因ID
- 5338
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NCBI登录号
- NM_002663, NP_002654
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UniProt
- O14939
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途径
- RTK signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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