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c-MYC 抗体 (N-Term)

Name: c-MYC 抗体 (N-Term)
SKU: ABIN2780430
Availability: OutOfStock

This anti-c-MYC antibody is a 兔多克隆 antibody detecting c-MYC in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 兔, 豚鼠和马.

WB Suggested Anti-MYC Antibody Titration: 1. (c-MYC 抗体 (N-Term))

IHC

2 images

产品编号 ABIN2780430

发货至: 中国

Quick Overview for c-MYC 抗体 (N-Term) (ABIN2780430)

抗原

See all c-MYC (MYC) 抗体

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 兔, 豚鼠, 马

宿主

兔

克隆类型

多克隆

标记

This c-MYC antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product MYC Primary Antibody

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N-Term

序列

MDFFRVVENQ QPPATMPLNV SFTNRNYDLD YDSVQPYFYC DEEENFYQQQ

预测反应

Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

产品特性

This is a rabbit polyclonal antibody against MYC. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human MYC
anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated

anti-Myc Proto-Oncogene protein (MYC) (Center) antibody
MYC 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 31-80) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody
MYC 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) antibody
KO Validated MYC 适用: 人 WB, IF, ChIP 宿主: 兔 Monoclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) antibody
MYC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 170 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

别名

Myc Proto-Oncogene protein

背景

MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this MYC gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Alias Symbols: MRTL, c-Myc, bHLHe39
Protein Interaction Partner: UBC, USP37, USP22, KDM1A, SKP2, SMAD7, SNRNP70, CEP57, LDOC1, BRD3, KIDINS220, MAX, CSNK2B, CSNK2A1, USP28, NMI, PFDN5, TP73, EP400, SP1, PIAS2, ZBTB17, IGF2BP3, PTRF, SDK1, MRPL53, PRKCDBP, PHLDB2, KNDC1, MZT2B, RIN3, NEK11, MICALL2, NLRX1, NABP2, MYC, M
Protein Size: 170

分子量

19 kDa

基因ID

4609

NCBI登录号

NM_002467

UniProt

P01106

途径

p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect