IRF1 抗体 (C-Term)
Quick Overview for IRF1 抗体 (C-Term) (ABIN2780409)
抗原
See all IRF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- YLLNEPGVQP TSVYGDFSCK EEPEIDSPGG DIGLSLQRVF TDLKNMDATW
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预测反应
- Cow: 86%, Dog: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against IRF1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of IRF1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 325 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IRF1 (Interferon Regulatory Factor 1 (IRF1))
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别名
- IRF1
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背景
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IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Alias Symbols: IRF-1, MAR
Protein Interaction Partner: SUMO2, SUMO3, IRF2, KAT2B, EP300, PRDM1, UBC, BIRC3, MDM2, HIST1H3A, CBL, HSP90AA1, HSPA1A, Tbk1, STUB1, SPI1, QARS, IRF8, CDKN1B, TRIM28, SET, SP2, IRF9, YBX1, NPM1, TRMT2A, HCFC1, SEC63, KEAP1, TRAF3, CREBBP, tat, SMARCA4, STAT1, HMGA1, RELA, NFKB1, KAT
Protein Size: 325 -
分子量
- 36 kDa
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基因ID
- 3659
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NCBI登录号
- NM_002198, NP_002189
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UniProt
- P10914
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途径
- Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
抗原
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