ATF4 抗体 (C-Term)
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- 抗原 See all ATF4 抗体
- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 豚鼠, 马, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATF4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EQNKTAATRY RQKKRAEQEA LTGECKELEK KNEALKERAD SLAKEIQYLK
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Sheep: 93%, Yeast: 82%
- 产品特性
- This is a rabbit polyclonal antibody against ATF4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ATF4
- Top Product
- Discover our top product ATF4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 351 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
- 别名
- ATF4 (ATF4 产品)
- 别名
- CREB-2 antibody, CREB2 antibody, TAXREB67 antibody, TXREB antibody, ATF4 antibody, atf-4 antibody, creb-2 antibody, creb2 antibody, taxreb67 antibody, txreb antibody, atf4 antibody, wu:fj01c08 antibody, wu:fk30b04 antibody, zgc:85951 antibody, sb:eu681 antibody, wu:fb08f07 antibody, zgc:171702 antibody, Atf-4 antibody, C/ATF antibody, ATF4-I antibody, atf4-a antibody, atf4-b antibody, atf4-ii antibody, activating transcription factor 4 antibody, activating transcription factor 4 L homeolog antibody, activating transcription factor 4a antibody, activating transcription factor 4b antibody, activating transcription factor 4 S homeolog antibody, ATF4 antibody, atf4 antibody, Atf4 antibody, atf4.L antibody, atf4a antibody, atf4b antibody, atf4.S antibody
- 背景
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ATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Alias Symbols: CREB2, TXREB, CREB-2, TAXREB67
Protein Interaction Partner: GPS2, GOLGA1, EP300, CEBPG, GOLGA8F, GOLGA8EP, GCC1, TRIB3, CCDC106, LDOC1, FBXW11, NDC80, BTRC, BFSP2, DDIT3, CREBBP, NEK6, JUN, FOS, ATF2, CEBPE, CEBPA, ATF4, ATF3, BATF2, CREBZF, BATF3, BATF, CREB3, MAFB, FOSL1, NFE2L2, NFE2, MAF, UBC, TGM2, RPS6, MAP2
Protein Size: 351 - 分子量
- 39 kDa
- 基因ID
- 468
- NCBI登录号
- NM_001675, NP_001666
- UniProt
- P18848
- 途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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