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FOXO3 抗体 (C-Term)

This anti-FOXO3 antibody is a 兔 多克隆 antibody detecting FOXO3 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马, 兔 和 豚鼠.
产品编号 ABIN2780367
发货至: 中国

Quick Overview for FOXO3 抗体 (C-Term) (ABIN2780367)

抗原

See all FOXO3 抗体
FOXO3 (Forkhead Box O3 (FOXO3))

适用

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人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马, 兔, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This FOXO3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    MESIIRSELM DADGLDFNFD SLISTQNVVG LNVGNFTGAK QASSQSWVPG

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%

    产品特性

    This is a rabbit polyclonal antibody against FOXO3A. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human FOXO3A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 453 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    FOXO3 (Forkhead Box O3 (FOXO3))

    别名

    FOXO3A

    背景

    FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.
    Alias Symbols: FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2
    Protein Interaction Partner: SMAD3, YWHAB, ERBB2IP, SIRT1, YWHAE, CDK6, AKT1, IKBKB, CHUK, CDT1, UBC, SKP2, MAPK1, PCNA, MDM2, BTRC, CREBBP, ELAVL1, SMAD4, MAPK6, NR1H3, NR1H2, NLK, VDR, SMAD1, EP300, STK4, FANCD2, RAD17, MYC, H2AFX, BRCA1, ATM, SIRT3, ATG101, YWHAH, PGK1, GBAS, FKBP
    Protein Size: 453

    分子量

    50 kDa

    基因ID

    2309

    NCBI登录号

    NM_001455

    UniProt

    Q68DV3

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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