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PPARD 抗体 (N-Term)

PPARD 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780303
发货至: 中国
  • 抗原 See all PPARD 抗体
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    抗原表位
    • 16
    • 13
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 82
    • 29
    • 19
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠
    宿主
    • 79
    • 10
    • 1
    克隆类型
    • 81
    • 9
    多克隆
    标记
    • 45
    • 11
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPARD antibody is un-conjugated
    应用范围
    • 80
    • 41
    • 28
    • 16
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    FGRMPEAEKR KLVAGLTASE GCQHNPQLAD LKAFSKHIYN AYLKNFNMTK
    预测反应
    Cow: 85%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 93%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against PPARD. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of mouse PPARD
    Top Product
    Discover our top product PPARD Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 440 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kramerova, Ermolova, Eskin, Hevener, Quehenberger, Armando, Haller, Romain, Nelson, Spencer: "Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy)." in: Human molecular genetics, Vol. 25, Issue 11, pp. 2194-2207, (2016) (PubMed).

    Ares-Carrasco, Picatoste, Camafeita, Carrasco-Navarro, Zubiri, Ortiz, Egido, López, Tuñón, Lorenzo: "Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPAR? in the associated hypertrophy." in: Journal of proteomics, Vol. 75, Issue 6, pp. 1816-29, (2012) (PubMed).

    Yang, Zhang, Zhou, Yan, Adell, Sun: "Biological function and prognostic significance of peroxisome proliferator-activated receptor ? in rectal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 11, pp. 3760-70, (2011) (PubMed).

    Yang, Olsson, Pfeifer, Jönsson, Zhou, Jiang, Fredriksson, Zhang, Sun: "Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells." in: Oncogene, Vol. 29, Issue 4, pp. 516-26, (2010) (PubMed).

  • 抗原
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    别名
    PPARD (PPARD 产品)
    别名
    FAAR antibody, NR1C2 antibody, NUC1 antibody, NUCI antibody, NUCII antibody, PPARB antibody, NUC-1 antibody, Nr1c2 antibody, PPAR-beta antibody, PPAR-delta antibody, PPAR[b] antibody, PPARdelta antibody, Pparb antibody, Pparb/d antibody, PPARBETA antibody, ppard antibody, pparb antibody, PPARD antibody, PPAR-D/B antibody, peroxisome proliferator activated receptor delta antibody, peroxisome proliferator activator receptor delta antibody, peroxisome proliferator activated receptor delta S homeolog antibody, peroxisome proliferator-activated receptor delta antibody, PPARD antibody, Ppard antibody, ppard.S antibody, ppard antibody
    背景
    PPARdelta is pivotal to control the program for fatty acid oxidation in the skeletal muscle, thereby ameliorating obesity and insulin resistance through its activation in obese animals.
    Alias Symbols: NUC1, NUC-1, Nr1c2, Pparb, PPAR[b], Pparb/d, PPAR-beta, PPARdelta, PPAR-delta
    Protein Interaction Partner: Scand1, HDAC7, NCOR2, BCL6, HSP90AA1, Apc, Rxrg, Rxra, Dut, GADD45A,
    Protein Size: 440
    分子量
    48 kDa
    基因ID
    19015
    NCBI登录号
    NM_011145, NP_035275
    UniProt
    P35396
    途径
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
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