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PPARD 抗体 (N-Term)

This anti-PPARD antibody is a 兔 多克隆 antibody detecting PPARD in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 兔. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN2780303
发货至: 中国

Quick Overview for PPARD 抗体 (N-Term) (ABIN2780303)

抗原

See all PPARD 抗体
PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔

宿主

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克隆类型

  • 76
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多克隆

标记

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This PPARD antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    FGRMPEAEKR KLVAGLTASE GCQHNPQLAD LKAFSKHIYN AYLKNFNMTK

    预测反应

    Cow: 85%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 93%, Mouse: 100%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PPARD. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of mouse PPARD
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 440 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kramerova, Ermolova, Eskin, Hevener, Quehenberger, Armando, Haller, Romain, Nelson, Spencer: "Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy)." in: Human molecular genetics, Vol. 25, Issue 11, pp. 2194-2207, (2016) (PubMed).

    Ares-Carrasco, Picatoste, Camafeita, Carrasco-Navarro, Zubiri, Ortiz, Egido, López, Tuñón, Lorenzo: "Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPAR? in the associated hypertrophy." in: Journal of proteomics, Vol. 75, Issue 6, pp. 1816-29, (2012) (PubMed).

    Yang, Zhang, Zhou, Yan, Adell, Sun: "Biological function and prognostic significance of peroxisome proliferator-activated receptor ? in rectal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 11, pp. 3760-70, (2011) (PubMed).

    Yang, Olsson, Pfeifer, Jönsson, Zhou, Jiang, Fredriksson, Zhang, Sun: "Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells." in: Oncogene, Vol. 29, Issue 4, pp. 516-26, (2010) (PubMed).

  • 抗原

    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

    别名

    PPARD

    背景

    PPARdelta is pivotal to control the program for fatty acid oxidation in the skeletal muscle, thereby ameliorating obesity and insulin resistance through its activation in obese animals.
    Alias Symbols: NUC1, NUC-1, Nr1c2, Pparb, PPAR[b], Pparb/d, PPAR-beta, PPARdelta, PPAR-delta
    Protein Interaction Partner: Scand1, HDAC7, NCOR2, BCL6, HSP90AA1, Apc, Rxrg, Rxra, Dut, GADD45A,
    Protein Size: 440

    分子量

    48 kDa

    基因ID

    19015

    NCBI登录号

    NM_011145, NP_035275

    UniProt

    P35396

    途径

    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
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