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MEF2C 抗体 (N-Term)

This anti-MEF2C antibody is a 兔 多克隆 antibody detecting MEF2C in WB. Suitable for 人, 小鼠, 大鼠, Pig, 斑马鱼, 犬, 马, 兔 和 Cow. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN2780048
发货至: 中国

Quick Overview for MEF2C 抗体 (N-Term) (ABIN2780048)

抗原

See all MEF2C 抗体
MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

适用

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人, 小鼠, 大鼠, Pig, 斑马鱼, 犬, 马, 兔, Cow

宿主

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克隆类型

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多克隆

标记

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This MEF2C antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    SRTNSDIVEA LNKKENKGSE SPDPDSSYAL TPRTEEKYKK INEEFDNMIK

    预测反应

    Cow: 86%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against MEF2C. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of mouse MEF2C
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 432 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Law, Leung, Yau, Tse, Wong, Leung, Mascheck, Huang, Sauer, Tsang et al.: "Regulation of multiple transcription factors by reactive oxygen species and effects of pro-inflammatory cytokines released during myocardial infarction on cardiac differentiation of embryonic stem ..." in: International journal of cardiology, Vol. 168, Issue 4, pp. 3458-72, (2013) (PubMed).

    Inagawa, Miyamoto, Yamakawa, Muraoka, Sadahiro, Umei, Wada, Katsumata, Kaneda, Nakade, Kurihara, Obata, Miyake, Fukuda, Ieda: "Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5." in: Circulation research, Vol. 111, Issue 9, pp. 1147-56, (2012) (PubMed).

    Escher, Schorderet, Cottet: "Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice." in: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5933-40, (2011) (PubMed).

    Blin, Nury, Stefanovic, Neri, Guillevic, Brinon, Bellamy, Rücker-Martin, Barbry, Bel, Bruneval, Cowan, Pouly, Mitalipov, Gouadon, Binder, Hagège, Desnos, Renaud, Menasché, Pucéat: "A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates." in: The Journal of clinical investigation, Vol. 120, Issue 4, pp. 1125-39, (2010) (PubMed).

    Lombardi, Dong, Rodriguez, Bell, Leung, Schwartz, Willerson, Brugada, Marian: "Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy." in: Circulation research, Vol. 104, Issue 9, pp. 1076-84, (2009) (PubMed).

    Leschik, Stefanovic, Brinon, Pucéat: "Cardiac commitment of primate embryonic stem cells." in: Nature protocols, Vol. 3, Issue 9, pp. 1381-7, (2008) (PubMed).

  • 抗原

    MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

    别名

    MEF2C

    背景

    MEF2C is a transcription regulator of slow fiber
    Alias Symbols: Mef2, AV011172, 5430401D19Rik, 9930028G15Rik
    Protein Interaction Partner: Vgll2, Hdac4, Nkx2-5, Hdac5, Phb2, KDM1A, Carm1, Ifrd1, Ncoa3, Ncoa2, Foxh1,
    Protein Size: 432

    分子量

    48 kDa

    基因ID

    17260

    NCBI登录号

    NM_025282, NP_079558

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling
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