T-Bet 抗体 (C-Term)
Quick Overview for T-Bet 抗体 (C-Term) (ABIN2780015)
抗原
See all T-Bet 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- MDPGLGSSEE QGSSPSLWPE VTSLQPESSD SGLGEGDTKR RRISPYPSSG
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预测反应
- Cow: 86%, Dog: 86%, Human: 93%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against TBX21. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of mouse TBX21
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 530 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- T-Bet
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别名
- TBX21
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背景
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TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Alias Symbols: TBT1, Tbet, Tblym
Protein Interaction Partner: Bcl6, Smarca4, Tlx3, Tead4, Pax9, Gsc, Gata3, Dlx1, Alx4, Rbpj, Stat1, Ifng, Tec, Itk, Txk,
Protein Size: 530 -
分子量
- 58 kDa
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基因ID
- 57765
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NCBI登录号
- NM_019507, NP_062380
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UniProt
- Q9JKD8
抗原
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