SREBF1 抗体 (N-Term)
Quick Overview for SREBF1 抗体 (N-Term) (ABIN2779970)
抗原
See all SREBF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DIEDMLQLIN NQDSDFPGLF DAPYAGGETG DTGPSSPGAN SPESFSSASL
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预测反应
- Mouse: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against SREBF1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of mouse SREBF1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1134 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
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别名
- SREBF1
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背景
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Srebf1 is transcriptional activator that binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Srebf1 also binds to an E-box motif (5'-ATCACGTGA-3'). Srebf1 regulates the transcription of genes for sterol biosynthesis and the LDL receptor gene.
Alias Symbols: ADD1, ADD-1, SREBP1, bHLHd1, SREBP-1, SREBP1c, SREBP-1a, SREBP-1c, D630008H06
Protein Interaction Partner: Rnf20, Zbtb7c, Ppargc1b, Rela, Ewsr1, Pcbd1,
Protein Size: 1134 -
分子量
- 125 kDa
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基因ID
- 20787
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NCBI登录号
- NM_011480, NP_035610
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UniProt
- Q9WTN3
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途径
- AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
抗原
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