MDC1 抗体 (C-Term)
Quick Overview for MDC1 抗体 (C-Term) (ABIN2779807)
抗原
See all MDC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GKEEDVVTPK PGKRKRDQAE EEPNRIPSRS LRRTKLNQES TAPKVLFTGV
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预测反应
- Dog: 86%, Guinea Pig: 92%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against MDC1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human MDC1
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anti-Mdc1 (MDC1) (AA 1-100) antibody
MDC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) antibodyMDC1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 31-130) antibodyMDC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 1-350) antibodyMDC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) (N-Term) antibodyMDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 unconjugated
anti-Mdc1 (MDC1) (N-Term) antibody (HRP)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 HRP
anti-Mdc1 (MDC1) (N-Term) antibody (FITC)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 FITC
anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 Biotin
anti-Mdc1 (MDC1) (N-Term) antibody (PE)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 PE
anti-Mdc1 (MDC1) (N-Term) antibody (APC)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 APC
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 2089 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MDC1 (Mdc1 (MDC1))
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别名
- MDC1
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背景
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The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
Alias Symbols: DKFZp781A0122, KIAA0170, MGC166888, NFBD1
Protein Interaction Partner: RPA3, RPA2, RPA1, EED, TOPBP1, RNF8, UBC, LMNA, RAG1, CDC27, NCL, NBN, MRE11A, CSNK2A1, RAD50, CAPZB, CAPZA1, AUP1, ATP2A2, LOC729324, CHAMP1, HNRNPUL2, PGAM5, LSM12, ANAPC16, OSBPL8, DTX2, ZNF251, RBM17, FAM175A, LAS1L, LPCAT1, MYH14, SLC25A22, ZNF768, H
Protein Size: 2089 -
分子量
- 227 kDa
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基因ID
- 9656
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NCBI登录号
- NM_014641, NP_055456
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UniProt
- Q14676
抗原
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