SMAD6 抗体 (C-Term)
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北京 101111
Quick Overview for SMAD6 抗体 (C-Term) (ABIN2779803)
抗原
See all SMAD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PDGVWAYNRG EHPIFVNSPT LDAPGGRALV VRKVPPGYSI KVFDFERSGL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against Smad6. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Smad6
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anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) antibody
SMAD6 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibodySMAD6 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A6 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 261-495) antibodySMAD6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-385) antibodySMAD6 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibodySMAD6 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 137-182) antibodySMAD6 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (N-Term) antibodySMAD6 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 358-386) antibodySMAD6 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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别名
- Smad6
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背景
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Smad6 binds to regulatory elements in target promoter regions. It may block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. It acts as a mediator of TGF-beta and BMP antiflammatory activity. It suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes.
Protein Interaction Partner: Smurf1, Tbx6, Bmpr2, Bmpr1a, Acvr1, Runx2, tob1a, Axin1, SMURF2, BMPR1B,
Protein Size: 459 -
分子量
- 54 kDa
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基因ID
- 17130
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UniProt
- O35182
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途径
- Chromatin Binding
抗原
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