我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

PTK2B 抗体 (C-Term)

Name: PTK2B 抗体 (C-Term)
SKU: ABIN2779800
Availability: OutOfStock

This anti-PTK2B antibody is a 兔多克隆 antibody detecting PTK2B in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, 马, Cow 和豚鼠. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-PTK2B Antibody Titration: 1. (PTK2B 抗体 (C-Term))

1 image

(1 reference)

产品编号 ABIN2779800

发货至: 中国

Quick Overview for PTK2B 抗体 (C-Term) (ABIN2779800)

抗原

See all PTK2B 抗体

PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

适用

人, 小鼠, 大鼠, 犬, 兔, 马, Cow, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This PTK2B antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product PTK2B Primary Antibody

抗原表位
24

21

15

10

7

6

4

4

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

序列

QKQMVEDYQW LRQEEKSLDP MVYMNDKSPL TPEKEVGYLE FTGPPQKPPR

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against PTK2B. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human PTK2B
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibody
PTK2B 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 1-1009) antibody
PTK2B 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibody
PTK2B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1F9 unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibody
PTK2B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) antibody
PTK2B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 805-838), (C-Term) antibody
PTK2B 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB50594 unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 812-861) antibody
PTK2B 适用: 人, 小鼠, 大鼠, 犬, 兔, Pig, 马, 猴, Cow, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibody
PTK2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal X1 unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 815-997) antibody
PTK2B 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5E2D5 unconjugated

anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (Tyr579) antibody
PTK2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1009 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Ling, Sheng, Braun: "The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation." in: American journal of physiology. Cell physiology, Vol. 287, Issue 3, pp. C698-706, (2004) (PubMed).
抗原

PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

别名

PTK2B

背景

PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.
Alias Symbols: PKB, PTK, CAKB, FAK2, PYK2, CADTK, FADK2, RAFTK
Protein Interaction Partner: CBLB, UBC, EGFR, PXN, HSP90AA1, MAPT, GP6, TRAF4, BCAR1, SKAP2, GP1BB, UL49, SOCS3, SRC, GRB2, FYN, DNM1, ALG2, SH3KBP1, PDCD6IP, CBL, SOCS2, PTEN, MBD2, DLGAP3, STAP1, SORBS2, NEDD9, EFS, NPHP1, PITPNM2, PITPNM3, PITPNM1, ARHGAP21, RB1CC1, ASAP1, LPXN, P
Protein Size: 1009

分子量

116 kDa

基因ID

2185

NCBI登录号

NM_004103, NP_004094

UniProt

Q14289

途径

EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling