TAF5L 抗体 (N-Term)
Quick Overview for TAF5L 抗体 (N-Term) (ABIN2779727)
抗原
See all TAF5L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LTDSDSQHSH EVMPLLYPLF VYLHLNLVQN SPKSTVESFY SRFHGMFLQN
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预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against TAF5L. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TAF5L
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 589 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TAF5L (TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L))
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别名
- TAF5L
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背景
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF5L encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF5. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation.
Alias Symbols: PAF65B
Protein Interaction Partner: HECW2, UBC, KAT2B, LSM11, TADA3, TAF10, ELAVL1, TSC22D1, TTR, H2AFX, CDKN1A, ANXA7, KAT2A, TP53, ATXN7, CEBPE, USP22, ATXN7L3, SUPT3H, TAF9, MYC,
Protein Size: 589 -
分子量
- 66 kDa
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基因ID
- 27097
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NCBI登录号
- NM_014409, NP_055224
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UniProt
- O75529
抗原
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