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FOXP1 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects FOXP1 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, 兔, Cow, 犬, 马 和 豚鼠. It has been mentioned in 3+ publications
产品编号 ABIN2779725
发货至: 中国
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Quick Overview for FOXP1 抗体 (N-Term) (ABIN2779725)

抗原

See all FOXP1 抗体
FOXP1 (Forkhead Box P1 (FOXP1))

适用

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人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠

宿主

  • 95
  • 18
  • 2

克隆类型

  • 72
  • 42
  • 1
多克隆

标记

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  • 3
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This FOXP1 antibody is un-conjugated

应用范围

  • 66
  • 46
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  • 38
  • 21
  • 18
  • 16
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  • 7
  • 2
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 12
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    • 8
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    N-Term

    序列

    MIPTELQQLW KEVTSAHTAE ETTGNNHSSL DLTTTCVSSS APSKTSLI

    预测反应

    Cow: 92%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against FOXP1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 677 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tang, Becanovic, Desplats, Spencer, Hill, Connolly, Masliah, Leavitt, Thomas: "Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease." in: Human molecular genetics, Vol. 21, Issue 14, pp. 3097-111, (2012) (PubMed).

    Konstantoulas, Parmar, Li: "FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3." in: Journal of neurochemistry, Vol. 113, Issue 4, pp. 836-47, (2010) (PubMed).

    Jepsen, Gleiberman, Shi, Simon, Rosenfeld: "Cooperative regulation in development by SMRT and FOXP1." in: Genes & development, Vol. 22, Issue 6, pp. 740-5, (2008) (PubMed).

  • 抗原

    FOXP1 (Forkhead Box P1 (FOXP1))

    别名

    FOXP1

    背景

    FOXP1 belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s).
    Alias Symbols: QRF1, 12CC4, hFKH1B, HSPC215
    Protein Interaction Partner: SUMO2, MYC, IL3RA, ELAVL1, NCOR2, GATAD2B, MTA1, FOXP1, FOXP4, FOXP2, CTBP1,
    Protein Size: 677

    分子量

    75 kDa

    基因ID

    27086

    NCBI登录号

    NM_032682, NP_116071

    UniProt

    Q9H334

    途径

    Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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