FOXP1 抗体 (N-Term)
Quick Overview for FOXP1 抗体 (N-Term) (ABIN2779725)
抗原
See all FOXP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MIPTELQQLW KEVTSAHTAE ETTGNNHSSL DLTTTCVSSS APSKTSLI
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预测反应
- Cow: 92%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against FOXP1. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 677 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease." in: Human molecular genetics, Vol. 21, Issue 14, pp. 3097-111, (2012) (PubMed).
: "FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3." in: Journal of neurochemistry, Vol. 113, Issue 4, pp. 836-47, (2010) (PubMed).
: "Cooperative regulation in development by SMRT and FOXP1." in: Genes & development, Vol. 22, Issue 6, pp. 740-5, (2008) (PubMed).
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: "Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease." in: Human molecular genetics, Vol. 21, Issue 14, pp. 3097-111, (2012) (PubMed).
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- FOXP1 (Forkhead Box P1 (FOXP1))
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别名
- FOXP1
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背景
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FOXP1 belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s).
Alias Symbols: QRF1, 12CC4, hFKH1B, HSPC215
Protein Interaction Partner: SUMO2, MYC, IL3RA, ELAVL1, NCOR2, GATAD2B, MTA1, FOXP1, FOXP4, FOXP2, CTBP1,
Protein Size: 677 -
分子量
- 75 kDa
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基因ID
- 27086
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NCBI登录号
- NM_032682, NP_116071
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UniProt
- Q9H334
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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