GFI1 抗体 (N-Term)
Quick Overview for GFI1 抗体 (N-Term) (ABIN2779720)
抗原
See all GFI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VPAPSRADST SNAGGAKAEP RDRLSPESQL TEAPDRASAS PDSCEGSVCE
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 79%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against GFI1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GFI1
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anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibody
GFI1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Growth Factor Independent 1 (GFI1) antibodyGFI1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) antibodyGFI1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D7 unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibodyGFI1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 280-330) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-422) antibodyGFI1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 32-81) antibodyGFI1 适用: 人, 大鼠, Cow, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 422 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GFI1 (Growth Factor Independent 1 (GFI1))
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别名
- GFI1
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背景
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GFI1 may be a transcription factor involved in regulating the expression of genes active in the S phase during cell cycle progression in T-cells. GFI1 may be involved in tumor progression. Defects in GFI1 are a cause of autosomal dominant severe congenital neutropenia (SCN) and dominant nonimmune chronic idiopathic neutropenia of adults (NI-CINA) This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Alias Symbols: ZNF163, SCN2, GFI-1
Protein Interaction Partner: RELA, SPI1, CHAF1A, PICK1, PIAS2, RCOR1, KDM1A, HDAC2, PRDM5, HDAC1, EHMT2, PIAS3, RUNX1T1, ARIH2, UBC,
Protein Size: 422 -
分子量
- 45 kDa
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基因ID
- 2672
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NCBI登录号
- NM_005263, NP_005254
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UniProt
- Q99684
抗原
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