c-FOS 抗体 (Middle Region)
Quick Overview for c-FOS 抗体 (Middle Region) (ABIN2779690)
抗原
See all c-FOS (c-Fos) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- PSVEPVKSIS SMELKTEPFD DFLFPASSRP SGSETARSVP DMDLSGSFYA
-
预测反应
- Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%
-
产品特性
- This is a rabbit polyclonal antibody against FOS. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FOS
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 380 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- c-FOS (c-Fos) (c-Fos)
-
别名
- FOS
-
背景
-
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: c-fos, p55, AP-1, C-FOS
Protein Interaction Partner: Psma4, CENPO, LMO3, ARFGAP1, USF2, USF1, PSMC5, PRKAA2, JUNB, JUN, GNG11, NQO1, ATF2, AQP1, LUZP4, CYTH4, CREB5, ABL1, CLU, ATP5I, APP, MTERF4, ANP32E, ARL6IP4, COPS4, CABP1, ZNF133, SET, NEFM, MAP1B, JUND, HSPA1A, MAF, FOS, DDIT3, CEBPG, CEBPE, CEBPA, AT
Protein Size: 380 -
分子量
- 41 kDa
-
基因ID
- 2353
-
NCBI登录号
- NM_005252, NP_005243
-
UniProt
- P01100
-
途径
- S100 Proteins
抗原
-