SIRT4 抗体 (N-Term)
Quick Overview for SIRT4 抗体 (N-Term) (ABIN2779655)
抗原
See all SIRT4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ASPPLDPEKV KELQRFITLS KRLLVMTGAG ISTESGIPDY RSEKVGLYAR
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against SIRT4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT4
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anti-Sirtuin 4 (SIRT4) (AA 28-314) antibody
SIRT4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 4 (SIRT4) (AA 51-150) antibodySIRT4 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 4 (SIRT4) (AA 60-255) antibodySIRT4 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 4 (SIRT4) (C-Term) antibodyVerified SIRT4 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sirtuin 4 (SIRT4) (AA 215-314) antibodySIRT4 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G6D2 unconjugated
anti-Sirtuin 4 (SIRT4) (Middle Region) antibodySIRT4 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 4 (SIRT4) (AA 29-260) antibodySIRT4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 4 (SIRT4) (AA 26-333) antibodySIRT4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 4 (SIRT4) (AA 215-314) antibodySIRT4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C8 unconjugated
anti-Sirtuin 4 (SIRT4) (AA 216-265) antibodySIRT4 适用: 人, 犬, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 314 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SIRT4 (Sirtuin 4 (SIRT4))
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别名
- SIRT4
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背景
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SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT4 is included in class IV of the sirtuin family. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Alias Symbols: MGC130046, MGC130047, MGC57437, SIR2L4, sirtuin 4
Protein Interaction Partner: SKP2, Glud1, UBC, SIRT3, IDE, SLC25A6, SLC25A5,
Protein Size: 314 -
分子量
- 35 kDa
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基因ID
- 23409
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NCBI登录号
- NM_012240, NP_036372
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UniProt
- Q9Y6E7
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途径
- Negative Regulation of Hormone Secretion
抗原
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