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Paired Box 3 抗体 (N-Term)

The 兔 多克隆 anti-Paired Box 3 antibody is suitable to detect Paired Box 3 in samples from 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔 和 Saccharomyces cerevisiae. It has been validated for WB.
产品编号 ABIN309659
发货至: 中国
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Quick Overview for Paired Box 3 抗体 (N-Term) (ABIN309659)

抗原

See all Paired Box 3 (PAX3) 抗体
Paired Box 3 (PAX3)

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This Paired Box 3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    DRNTVPSVSS ISRILRSKFG KGEEEEADLE RKEAEESEKK AKHSIDGILS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

    产品特性

    This is a rabbit polyclonal antibody against PAX3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PAX3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 484 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Paired Box 3 (PAX3)

    别名

    PAX3

    背景

    PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
    Alias Symbols: CDHS, HUP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, WS1, WS3
    Protein Interaction Partner: PCTP, UBC, TAF1, POU3F2, HDAC1, TRIM28, HDAC10, SOX8, WWTR1, PAX3, DAXX, CIB1, SOX10, MEOX2, MEOX1, MITF, MSX1, Rad23b, PSMD4, TBP, IPO13, CNR1,
    Protein Size: 484

    分子量

    53 kDa

    基因ID

    5077

    NCBI登录号

    NM_181458, NP_852123

    UniProt

    Q494Z3

    途径

    Sensory Perception of Sound, Tube Formation
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