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ZEB1 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-ZEB1 antibody is suitable to detect ZEB1 in samples from 人, 小鼠, 大鼠, 兔, 犬, Cow 和 豚鼠. It has been validated for WB 和 IF.
产品编号 ABIN2779631
发货至: 中国
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Quick Overview for ZEB1 抗体 (N-Term) (ABIN2779631)

抗原

See all ZEB1 抗体
ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

适用

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人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠

宿主

  • 44
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克隆类型

  • 30
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多克隆

标记

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This ZEB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    N-Term

    序列

    KDDECESDAE NEQNHDPNVE EFLQQQDTAV IFPEAPEEDQ RQGTPEASGH

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ZEB1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ZEB1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1124 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lobert, Graichen, Morris: "Coordinated regulation of ?-tubulin isotypes and epithelial-to-mesenchymal transition protein ZEB1 in breast cancer cells." in: Biochemistry, Vol. 52, Issue 32, pp. 5482-90, (2013) (PubMed).

  • 抗原

    ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

    别名

    ZEB1

    背景

    ZEB1 is a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site.ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM].
    Alias Symbols: AREB6, BZP, MGC133261, NIL-2-A, NIL-2A, TCF8, ZEB, ZFHEP, ZFHX1A, FECD6, NIL2A, PPCD3, DELTAEF1
    Protein Interaction Partner: SUMO1, CDK6, GTF2A1, UBR4, SUMO2, SIRT1, SOX2, CTBP2, CTBP1, SMAD7, SMAD6, SMARCA4, SERPINH1, SMAD3, EP300, DRAP1, KAT5, SMAD2, SMAD1, CDH1,
    Protein Size: 1124

    分子量

    124 kDa

    基因ID

    6935

    NCBI登录号

    NM_030751, NP_110378

    UniProt

    P37275

    途径

    Regulation of Muscle Cell Differentiation
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