TAB2 抗体 (N-Term)
(1 reference)Quick Overview for TAB2 抗体 (N-Term) (ABIN2779619)
抗原
See all TAB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QKFPEVPEVV VSRCMLQNNN NLDACCAVLS QESTRYLYGE GDLNFSDDSG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against MAP3K7IP2. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K7IP2
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (N-Term) antibody
TAB2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) antibodyTAB2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) antibodyTAB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 646-680), (C-Term) antibodyTAB2 适用: 大鼠 WB 宿主: 兔 Polyclonal RB52974 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 1-693) antibodyTAB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 1-693) antibodyTAB2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (Internal Region) antibodyTAB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 350-693) antibodyTAB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 693 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Haploinsufficiency of TAB2 causes congenital heart defects in humans." in: American journal of human genetics, Vol. 86, Issue 6, pp. 839-49, (2010) (PubMed).
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: "Haploinsufficiency of TAB2 causes congenital heart defects in humans." in: American journal of human genetics, Vol. 86, Issue 6, pp. 839-49, (2010) (PubMed).
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- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
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别名
- MAP3K7IP2
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背景
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MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Alias Symbols: CHTD2, MAP3K7IP2
Protein Interaction Partner: UBC, PIAS3, UBE2I, TRAF6, SUMO2, IRAK1, MAP3K7, TRIM38, SIK1, SIK3, TRIM22, NPM1, CST9L, SLC19A3, env, TAB1, NUMBL, IKBKG, FOSL1, ZBTB16, YWHAZ, VIM, TGM2, PPP2CB, IKBKB, GTF2I, FN1, HSP90AA1, BST2, MALT1, WDR34, APP, ESR1, MAP3K8, AR, TRIM5, TBL1XR1, MBD
Protein Size: 693 -
分子量
- 76 kDa
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基因ID
- 23118
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NCBI登录号
- NM_015093, NP_055908
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UniProt
- Q9NYJ8
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途径
- TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
抗原
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