SIRT2 抗体 (C-Term)
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- 抗原 See all SIRT2 抗体
- SIRT2 (Sirtuin 2 (SIRT2))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠, 兔, 犬, 豚鼠, Cow, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIRT2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DVAWLGECDQ GCLALAELLG WKKELEDLVR REHASIDAQS GAGVPNPSTS
- 预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%, Zebrafish: 75%
- 产品特性
- This is a rabbit polyclonal antibody against SIRT2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT2
- Top Product
- Discover our top product SIRT2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 352 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SIRT2 (Sirtuin 2 (SIRT2))
- 别名
- SIRT2 (SIRT2 产品)
- 背景
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SIRT2 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT2 is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene.
Alias Symbols: SIR2, SIR2L, SIR2L2
Protein Interaction Partner: ACLY, SIRT1, UBC, ING1, EP300, CBLB, CBL, XPO1, CDC20, FZR1, RUNX3, PCK1, FOXO1, HDAC6, tat, RBP1, HIST1H3A, NUDT21, PAPOLA, DNAJB8, DNAJB6, SP140, KAT2B, CDC14B, KAT2A, TUBA4A, HOXA10, TUBB, KRT78, RTN4, PHB2, SPOP, ELL, SARS, GYS1,
Protein Size: 352 - 分子量
- 40 kDa
- 基因ID
- 22933
- NCBI登录号
- NM_030593, NP_085096
- UniProt
- Q8IXJ6
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