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TLE1 抗体 (N-Term)

TLE1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779588
发货至: 中国
  • 抗原 See all TLE1 抗体
    TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
    抗原表位
    • 12
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 58
    • 11
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔
    宿主
    • 41
    • 17
    • 1
    克隆类型
    • 41
    • 18
    多克隆
    标记
    • 37
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLE1 antibody is un-conjugated
    应用范围
    • 47
    • 25
    • 13
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    RNGPEFSNDI KKRKVDDKDS SHYDSDGDKS DDNLVVDVSN EDPSSPRASP
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against TLE1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TLE1
    Top Product
    Discover our top product TLE1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 770 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
    别名
    TLE1 (TLE1 产品)
    背景
    TLE1 is a transcriptional corepressor that binds to a number of transcription factors. TLE1 inhibits NF-kappa-B-regulated gene expression and the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE1 has an unusual function as coactivator for ESRRG.
    Alias Symbols: ESG, ESG1, GRG1
    Protein Interaction Partner: TLE1, TCF3, TCF4, UBC, SS18, SSX2, HDAC1, EZH2, ATF2, APH1A, LEF1, TLX3, PROP1, HES1, TLX1, HHEX, FOXG1, ESRRG, EN1, tcf7l1a, NOD2, AES, HESX1, GSK3B, GRB7, NUDT21, DAZAP2, KIAA0408, TSC22D1, TK1, SMN1, RAP1B, GADD45A, CSNK2B, RCC1, CDKN1A, BID, BCL2L1, A
    Protein Size: 770
    分子量
    83 kDa
    基因ID
    7088
    NCBI登录号
    NM_005077, NP_005068
    UniProt
    Q04724
    途径
    WNT signaling, SARS-CoV-2 Protein Interactome
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