TLE1 抗体 (N-Term)
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- 抗原 See all TLE1 抗体
- TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TLE1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RNGPEFSNDI KKRKVDDKDS SHYDSDGDKS DDNLVVDVSN EDPSSPRASP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against TLE1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TLE1
- Top Product
- Discover our top product TLE1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 770 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
- 别名
- TLE1 (TLE1 产品)
- 背景
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TLE1 is a transcriptional corepressor that binds to a number of transcription factors. TLE1 inhibits NF-kappa-B-regulated gene expression and the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE1 has an unusual function as coactivator for ESRRG.
Alias Symbols: ESG, ESG1, GRG1
Protein Interaction Partner: TLE1, TCF3, TCF4, UBC, SS18, SSX2, HDAC1, EZH2, ATF2, APH1A, LEF1, TLX3, PROP1, HES1, TLX1, HHEX, FOXG1, ESRRG, EN1, tcf7l1a, NOD2, AES, HESX1, GSK3B, GRB7, NUDT21, DAZAP2, KIAA0408, TSC22D1, TK1, SMN1, RAP1B, GADD45A, CSNK2B, RCC1, CDKN1A, BID, BCL2L1, A
Protein Size: 770 - 分子量
- 83 kDa
- 基因ID
- 7088
- NCBI登录号
- NM_005077, NP_005068
- UniProt
- Q04724
- 途径
- WNT signaling, SARS-CoV-2 Protein Interactome
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