TLE2 抗体 (N-Term)
Quick Overview for TLE2 抗体 (N-Term) (ABIN2779582)
抗原
See all TLE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VEEERPSGPG GGGKQRADEK EPSGPYESDE DKSDYNLVVD EDQPSEPPSP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against TLE2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TLE2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 743 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
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别名
- TLE2
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背景
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TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: ESG, ESG2, FLJ41188, GRG2
Protein Interaction Partner: UBC, SUMO1, ORF50, LEF1, BARHL1, TLX3, VENTX, CUL4A, CUL4B, PAX9, MSX2, MSX1, FOXA3, EMX2, PRDM1, H3F3B, TLE1, UTY, HMGB1, RUNX1, TLE2, HES1,
Protein Size: 743 -
分子量
- 80 kDa
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基因ID
- 7089
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NCBI登录号
- NM_003260, NP_003251
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UniProt
- Q04725
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途径
- WNT signaling
抗原
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