电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Nkx2-2 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-Nkx2-2 antibody specifically detects Nkx2-2 in IHC 和 WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 和 绵羊 samples.
产品编号 ABIN2779575
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Nkx2-2 抗体 (N-Term) (ABIN2779575)

抗原

See all Nkx2-2 抗体
Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

适用

  • 135
  • 53
  • 49
  • 24
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊

宿主

  • 84
  • 58

克隆类型

  • 93
  • 49
多克隆

标记

  • 57
  • 13
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This Nkx2-2 antibody is un-conjugated

应用范围

  • 78
  • 60
  • 48
  • 32
  • 28
  • 24
  • 13
  • 13
  • 12
  • 8
  • 7
  • 3
Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

    • 34
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    MSLTNTKTGF SVKDILDLPD TNDEEGSVAE GPEEENEGPE PAKRAGPLGQ

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against NKX2-2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human NKX2-2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 273 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Owen, Kowalewski, Lessnick: "EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma." in: PLoS ONE, Vol. 3, Issue 4, pp. e1965, (2008) (PubMed).

  • 抗原

    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

    别名

    NKX2-2

    背景

    Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2. Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
    Alias Symbols: NKX2.2, NKX2B
    Protein Interaction Partner: Dlg4, SIN3A, HDAC1, OLIG2,
    Protein Size: 273

    分子量

    30 kDa

    基因ID

    4821

    NCBI登录号

    NM_002509, NP_002500

    UniProt

    O95096

    途径

    Dopaminergic Neurogenesis
You are here: