ISL1 抗体 (N-Term)
Quick Overview for ISL1 抗体 (N-Term) (ABIN2779574)
抗原
See all ISL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- IECFRCVACS RQLIPGDEFA LREDGLFCRA DHDVVERASL GAGDPLSPLH
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against ISL1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ISL1
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anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibody
ISL1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibodyISL1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1H9 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 1A1 unconjugated Recombinant Antibody
anti-ISL LIM Homeobox 1 (ISL1) antibodyMicroarray verified ISL1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB381223 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 1-346) antibodyISL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibodyISL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A7 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, IF, ICC, IHC (p), IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibodyISL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 349 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ISL1 (ISL LIM Homeobox 1 (ISL1))
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别名
- ISL1
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背景
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ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Isl-1, ISLET1
Protein Interaction Partner: ZNF511, KDM1A, RELA, SMAD3, CDKN2B, CDK6, APP, COPS5, SSBP4, LHX4, LDB2, ISL2, PECR, LDB1, LHX1, LHX3, LMX1A, RLIM, LMO2, ESR1, NR2F1, ISL1,
Protein Size: 349 -
分子量
- 39 kDa
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基因ID
- 3670
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NCBI登录号
- NM_002202, NP_002193
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UniProt
- P61371
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途径
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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